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Daniel Aberdam completed his first degrees at Pierre and Marie Curie University (Paris, France) and his PhD at the Weizmann Institute (Israël) on the oncogenic potential of homeotic genes, under the supervision of Professor Leo Sachs. He currently holds the position of INSERM Director of Research and Long Term Visiting Professor of the Israeli Institute of Technology (Technion). He is Director of the INSERM Unit U898 (Nice, France) and Director of INSERTECH (Technion). His scientific interests focus on epithelial gene regulation and skin physiopathology. Lately, his group developed strategies to recapitulate in vitro embryonic skin development derived from embryonic stem cell lines. The current projects developed by his teams are centered around the function and regulation of p63, a p53-related epithelial master gene and the use of pluripotent stem cells as cellular models and for cell and gene therapies

Gustavo P Amarante-Mendes received his MSc and PhD in Immunology at the University of São Paulo (São Paulo, Brazil). As part of the PhD program, he spent two years at the Institut Armand-Frappier (Montreal, Canada) working on thymocyte differentiation and apoptosis. From 1995 to 1997 he conducted postdoctoral research at the La Jolla Institute for Allergy and Immunology (San Diego, USA), working on the molecular mechanisms that control apoptosis in cancer. In 1998 he was appointed Assistant Professor at the Institute of Biomedical Sciences, University of São Paulo, where he became Associate Professor in 2009. He spent one year between 2003 and 2004 at the Smurfit Institute of Genetics, at Trinity College Dublin (Dublin, Ireland) working on proteomics of cytotoxic cell granules. His current scientific interests are related to signaling pathways controlling cell death in cancer and in the immune system.

Rami Aqeilan received his PhD from the Hebrew University of Jerusalem. He completed his postdoctoral training in the laboratory of Dr Carlo Croce at Thomas Jefferson University in Philadelphia and at Ohio State University in Columbus. He joined the Hebrew University of Jerusalem as a Senior Lecturer in 2008. Dr Aqeilan's laboratory investigates the physiological role of the WW domain-containing oxidoreductase (WWOX) in tumour suppression, progression, DNA damage response, and resistance to anti-cancer treatments. His laboratory also studies the regulation of the Hippo tumor suppressor pathway and its involvement in organ size and tumorigenesis.

After obtaining his MD in Tucuman, Argentina, Dr Nicolas Bazan was a postdoc at P&S, Columbia University, and Harvard Medical School. In his first lab at the Clarke Institute of Psychiatry, Toronto, he found that ischemia or seizures cause an increase in free arachidonic and docosahexaenoic acid pools in the brain. He then discovered that the lipid mediator platelet activating factor (PAF) is released by injury and that PAF antagonism is protective in experimental stroke. He identified PAF binding in synaptic and intracellular membranes; defined PAF-mediated regulation of early gene expression; and found that PAF mediates long-term potentiation and memory. He also uncovered that the supply of the omega-3 fatty acid DHA to synapses is liver-regulated and that DHA is retained in photoreceptors by a "short loop" (RPE-to-photoreceptors) and a "long loop" (liver-to-retina). He found that Usher's Syndrome patients have DHA shortage in the blood, implicating the long loop in retinal degenerations. He and his colleagues discovered the synthesis and bioactivity of neuroprotectin D1, which arrests apoptosis at the pre-mitochondrial level, is anti-inflammatory, and is neuroprotective in experimental stroke and Alzheimer's disease models. He found NPD1 is decreased in the CA1 area of Alzheimer's patients. The recognitions he has received include the Javits Neuroscience Award, NINDS, NIH; elected to Royal Academy of Medicine, Spain; elected fellow, Royal College of Physicians of Ireland, Dublin; and Proctor Medal, the highest honour of The Association for Research in Vision and Ophthalmology. He is the founding director of the LSU Neuroscience Center of Excellence, New Orleans. Dr Bazan's research focuses on synaptic signaling in neuronal plasticity, cell survival signaling in epilepsy and ischemia-reperfusion, and inflammatory signaling in Alzheimer's and other neurodegenerations.